# 5-Amino-1MQ: Reference Overview and Reconstitution Notes - facts

Canonical page: https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq
Type: Lab article

## TL;DR

5-Amino-1MQ is a synthetic small molecule, not a peptide, studied as an inhibitor of the enzyme NNMT. Overview, classification and reconstitution notes.

## Facts Index

| Fact ID | Category | Entity | Attribute | Value | Source | Evidence |
|---|---|---|---|---|---|---|
| 5-amino-1mq:title | identity | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | title | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:published | identity | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | published | 2026-08-15 | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:last-reviewed | identity | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | last reviewed | 2026-10-03 | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:author | identity | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | author | Preppin' Peppers Editorial Team | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:topics | identity | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | topics | research, Research-only | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:summary | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | summary | 5-Amino-1MQ is a synthetic small molecule, not a peptide, studied as an inhibitor of the enzyme NNMT. Overview, classification and reconstitution notes. | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:section-1 | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:section-2 | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | section | 5-Amino-1MQ | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:section-3 | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:section-4 | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | section | Research context and categorization | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:section-5 | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | section | Status | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:section-6 | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | section | Reconstitution notes (general) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:section-7 | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | section | Dilution and handling notes (compound-specific) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:section-8 | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | section | Handling and storage | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:section-9 | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | section | Related reading | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:section-10 | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | section | Tools and supplies | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:section-12 | content | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | section | What the research community gets wrong about 5-Amino-1MQ | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq |
| 5-amino-1mq:product-gansulin-metal-peptide-pen | products | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | references product | Gansulin Pen · Reusable Click-Dial, 3 ml (1-60 Units) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/products/gansulin-metal-peptide-pen |
| 5-amino-1mq:product-gansulin-3ml-cartridge | products | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | references product | Gansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.preppinpeppers.com/products/gansulin-3ml-cartridge |
| 5-amino-1mq:source-pubchem-ncbi-nlm-nih-gov | source | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | cites | NCBI PubChem CID 950107: 5-Amino-1-methylquinolinium (C10H11N2+) - pubchem.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://pubchem.ncbi.nlm.nih.gov/compound/950107 |
| 5-amino-1mq:source-pubmed-ncbi-nlm-nih-gov | source | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | cites | Neelakantan et al., Biochem Pharmacol 2018: Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://pubmed.ncbi.nlm.nih.gov/29155147/ |
| 5-amino-1mq:source-pmc-ncbi-nlm-nih-gov | source | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | cites | Dimet-Wiley et al., Sci Rep 2022: Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice - pmc.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://pmc.ncbi.nlm.nih.gov/articles/PMC8748953/ |
| 5-amino-1mq:source-www-uniprot-org | source | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | cites | UniProtKB/Swiss-Prot P40261: Nicotinamide N-methyltransferase (NNMT, Homo sapiens), UniProt release 2026-03 - www.uniprot.org | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://www.uniprot.org/uniprotkb/P40261/entry |
| 5-amino-1mq:source-pmc-ncbi-nlm-nih-gov-2 | source | 5-Amino-1MQ: Reference Overview and Reconstitution Notes | cites | Yang et al., J Immunother Cancer 2024: NAD(+) metabolism enzyme NNMT in cancer-associated fibroblasts drives tumor progression and resistance to immunotherapy by modulating macrophages in urothelial bladder cancer - pmc.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/5-amino-1mq) | https://pmc.ncbi.nlm.nih.gov/articles/PMC11284830/ |

## FAQ

### What is 5-Amino-1MQ and how does it work?

5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic, cell-permeable compound that selectively inhibits NNMT, an enzyme that diverts nicotinamide away from NAD+ synthesis; it is studied in preclinical metabolism research only.

### What is the regulatory classification of 5-Amino-1MQ?

No. It is not approved by any regulator for any use. As of 2026, no IND application or registered human clinical trial is on record. It is classified as research-only and is not a controlled substance under the U.S. Controlled Substances Act.

### Is 5-Amino-1MQ on the WADA prohibited list?

It is not listed by name, but as an unapproved pharmacological substance it may fall under S0 (Non-Approved Substances) or S4 (Hormone and Metabolic Modulators). Athletes subject to anti-doping testing should consult a qualified professional.

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