# Cortagen: Reference Overview and Reconstitution Notes - facts

Canonical page: https://www.preppinpeppers.com/blogs/the-lab/cortagen
Type: Lab article

## TL;DR

Cortagen is a synthetic brain-cortex tetrapeptide in the Khavinson bioregulator family, classed under neural and anti-aging research. Research use only.

## Facts Index

| Fact ID | Category | Entity | Attribute | Value | Source | Evidence |
|---|---|---|---|---|---|---|
| cortagen:title | identity | Cortagen: Reference Overview and Reconstitution Notes | title | Cortagen: Reference Overview and Reconstitution Notes | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:published | identity | Cortagen: Reference Overview and Reconstitution Notes | published | 2026-08-15 | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:author | identity | Cortagen: Reference Overview and Reconstitution Notes | author | Preppin' Peppers Editorial Team | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:topics | identity | Cortagen: Reference Overview and Reconstitution Notes | topics | research, Research-only | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:summary | content | Cortagen: Reference Overview and Reconstitution Notes | summary | Cortagen is a synthetic brain-cortex tetrapeptide in the Khavinson bioregulator family, classed under neural and anti-aging research. Research use only. | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:section-1 | content | Cortagen: Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:section-2 | content | Cortagen: Reference Overview and Reconstitution Notes | section | Research context and categorization | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:section-3 | content | Cortagen: Reference Overview and Reconstitution Notes | section | Status | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:section-4 | content | Cortagen: Reference Overview and Reconstitution Notes | section | Reconstitution notes (general) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:section-5 | content | Cortagen: Reference Overview and Reconstitution Notes | section | Dilution and handling notes (compound-specific) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:section-6 | content | Cortagen: Reference Overview and Reconstitution Notes | section | Handling and storage | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:section-7 | content | Cortagen: Reference Overview and Reconstitution Notes | section | Related reading | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:section-8 | content | Cortagen: Reference Overview and Reconstitution Notes | section | Tools and supplies | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:section-10 | content | Cortagen: Reference Overview and Reconstitution Notes | section | What the research community gets wrong about Cortagen | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/blogs/the-lab/cortagen |
| cortagen:product-gansulin-metal-peptide-pen | products | Cortagen: Reference Overview and Reconstitution Notes | references product | Gansulin Pen · Reusable Click-Dial, 3 ml (1-60 Units) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/products/gansulin-metal-peptide-pen |
| cortagen:product-gansulin-3ml-cartridge | products | Cortagen: Reference Overview and Reconstitution Notes | references product | Gansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://www.preppinpeppers.com/products/gansulin-3ml-cartridge |
| cortagen:source-pubchem-ncbi-nlm-nih-gov | source | Cortagen: Reference Overview and Reconstitution Notes | cites | NCBI PubChem CID 18439621: Cortagen (C17H26N4O9) - pubchem.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://pubchem.ncbi.nlm.nih.gov/compound/18439621 |
| cortagen:source-pubmed-ncbi-nlm-nih-gov | source | Cortagen: Reference Overview and Reconstitution Notes | cites | Turchaninova et al., Bull Exp Biol Med 2000: Effect of tetrapeptide cortagen on regeneration of sciatic nerve - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://pubmed.ncbi.nlm.nih.gov/11276314/ |
| cortagen:source-pubmed-ncbi-nlm-nih-gov-2 | source | Cortagen: Reference Overview and Reconstitution Notes | cites | Anisimov et al., Neuro Endocrinol Lett 2004: Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://pubmed.ncbi.nlm.nih.gov/15159690/ |
| cortagen:source-pubmed-ncbi-nlm-nih-gov-3 | source | Cortagen: Reference Overview and Reconstitution Notes | cites | Kolosova et al., Dokl Biol Sci 2002: The delayed effect of cortagen on the restoration of injured nerve function - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://pubmed.ncbi.nlm.nih.gov/12134478/ |
| cortagen:source-pubmed-ncbi-nlm-nih-gov-4 | source | Cortagen: Reference Overview and Reconstitution Notes | cites | Tutel'yan et al., Bull Exp Biol Med 2003: Physiological role of short peptides in nutrition - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/cortagen) | https://pubmed.ncbi.nlm.nih.gov/12717498/ |

## FAQ

### What is Cortagen and what is its amino acid sequence?

Cortagen is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Pro (AEDP), derived from cortexin-based research. It belongs to the Khavinson bioregulator family and is investigated as a neural/brain-cortex research compound.

### Is Cortagen prohibited under WADA anti-doping rules?

Cortagen is not approved by any regulator, including the FDA, and is classified as research-only. It is not specifically named on the WADA Prohibited List, but the catch-all S0 category may apply because it is an experimental research peptide that is not a licensed product. Confirm status with WADA directly.

### How do you calculate peptide concentration when reconstituting a lyophilized vial?

Divide the milligrams of peptide in the vial by the volume of bacteriostatic water added in milliliters. The result is the concentration in mg/mL. This arithmetic applies to any lyophilized research peptide reconstituted in aqueous solvent.

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