{
    "schema": 1,
    "fid": "dsip",
    "type": "article",
    "object_id": 372,
    "title": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
    "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
    "url": "https://www.preppinpeppers.com/blogs/the-lab/dsip",
    "facts_url": "https://www.preppinpeppers.com/facts/dsip",
    "currency": null,
    "tldr": "DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nine-amino-acid neuropeptide studied in sleep and neuroendocrine research. Not FDA-approved.",
    "facts": [
        {
            "id": "dsip:title",
            "category": "identity",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "title",
            "value": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:published",
            "category": "identity",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "published",
            "value": "2026-08-15",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:author",
            "category": "identity",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "author",
            "value": "Preppin' Peppers Editorial Team",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:topics",
            "category": "identity",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "topics",
            "value": "research, Research-only",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:summary",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "summary",
            "value": "DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nine-amino-acid neuropeptide studied in sleep and neuroendocrine research. Not FDA-approved.",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:section-1",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "section",
            "value": "What it is",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:section-2",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "section",
            "value": "DSIP (Delta Sleep-Inducing Peptide)",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:section-3",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "section",
            "value": "What it is",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:section-4",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "section",
            "value": "Research context and categorization",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:section-5",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "section",
            "value": "Status",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:section-6",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "section",
            "value": "Reconstitution notes (general)",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:section-7",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "section",
            "value": "Dilution and handling notes (compound-specific)",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:section-8",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "section",
            "value": "Handling and storage",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:section-9",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "section",
            "value": "Related reading",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:section-10",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "section",
            "value": "Tools and supplies",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:section-12",
            "category": "content",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "section",
            "value": "What the research community gets wrong about DSIP handling",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/blogs/the-lab/dsip"
        },
        {
            "id": "dsip:product-gansulin-metal-peptide-pen",
            "category": "products",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "references product",
            "value": "Gansulin Pen · Reusable Click-Dial, 3 ml (1-60 Units)",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/products/gansulin-metal-peptide-pen"
        },
        {
            "id": "dsip:product-gansulin-3ml-cartridge",
            "category": "products",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "references product",
            "value": "Gansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack)",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://www.preppinpeppers.com/products/gansulin-3ml-cartridge"
        },
        {
            "id": "dsip:source-pubmed-ncbi-nlm-nih-gov",
            "category": "source",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "cites",
            "value": "Graf and Kastin, Neurosci Biobehav Rev 1984: Delta-sleep-inducing peptide (DSIP): a review - pubmed.ncbi.nlm.nih.gov",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://pubmed.ncbi.nlm.nih.gov/6145137/"
        },
        {
            "id": "dsip:source-pubmed-ncbi-nlm-nih-gov-2",
            "category": "source",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "cites",
            "value": "Schoenenberger et al., Pflugers Arch 1978: The delta EEG (sleep)-inducing peptide (DSIP). XI. Amino-acid analysis, sequence, synthesis and activity of the nonapeptide - pubmed.ncbi.nlm.nih.gov",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://pubmed.ncbi.nlm.nih.gov/568769/"
        },
        {
            "id": "dsip:source-pubchem-ncbi-nlm-nih-gov",
            "category": "source",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "cites",
            "value": "NCBI PubChem CID 68816: Delta Sleep-Inducing Peptide (C35H48N10O15) - pubchem.ncbi.nlm.nih.gov",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://pubchem.ncbi.nlm.nih.gov/compound/68816"
        },
        {
            "id": "dsip:source-pubmed-ncbi-nlm-nih-gov-3",
            "category": "source",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "cites",
            "value": "Pollard and Pomfrett, Eur J Anaesthesiol 2001: Delta sleep-inducing peptide - pubmed.ncbi.nlm.nih.gov",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://pubmed.ncbi.nlm.nih.gov/11437870/"
        },
        {
            "id": "dsip:source-pubmed-ncbi-nlm-nih-gov-4",
            "category": "source",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "cites",
            "value": "Graf et al., Pharmacol Biochem Behav 1984: DSIP occurs in free form in mammalian plasma, human CSF and urine - pubmed.ncbi.nlm.nih.gov",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://pubmed.ncbi.nlm.nih.gov/6549071/"
        },
        {
            "id": "dsip:source-pubmed-ncbi-nlm-nih-gov-5",
            "category": "source",
            "entity": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "attribute": "cites",
            "value": "Gimble et al., Obes Rev 2009: Delta sleep-inducing peptide and glucocorticoid-induced leucine zipper: potential links between circadian mechanisms and obesity? - pubmed.ncbi.nlm.nih.gov",
            "source": "Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip)",
            "evidence": "https://pubmed.ncbi.nlm.nih.gov/19849801/"
        }
    ],
    "buy": [],
    "faq": [
        {
            "q": "What is the chemical structure of DSIP?",
            "a": "DSIP is a nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, molecular weight ~850 daltons, and an amphipathic structure. Lab-grade material is produced by chemical synthesis."
        },
        {
            "q": "Is DSIP FDA-approved or banned in sport?",
            "a": "DSIP is not FDA-approved for any condition. It is not named on the WADA Prohibited List but may fall under class S0 (Non-Approved Substances). Athletes subject to testing should consult their anti-doping authority."
        },
        {
            "q": "How do researchers reconstitute lyophilized DSIP for laboratory use?",
            "a": "Add a measured volume of bacteriostatic water to the lyophilized vial, then calculate working concentration by dividing mg of peptide by mL of water added (e.g., 5 mg ÷ 2.5 mL = 2 mg/mL)."
        }
    ],
    "jsonld": [
        {
            "@context": "https://schema.org",
            "@type": "Article",
            "headline": "DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes",
            "url": "https://www.preppinpeppers.com/blogs/the-lab/dsip",
            "mainEntityOfPage": "https://www.preppinpeppers.com/blogs/the-lab/dsip",
            "datePublished": "2026-08-15",
            "dateModified": "2026-10-16",
            "author": {
                "@type": "Person",
                "name": "Preppin' Peppers Editorial Team"
            },
            "publisher": {
                "@type": "Organization",
                "name": "PreppinPeppers"
            },
            "description": "DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nine-amino-acid neuropeptide studied in sleep and neuroendocrine research. Not FDA-approved."
        },
        {
            "@context": "https://schema.org",
            "@type": "FAQPage",
            "url": "https://www.preppinpeppers.com/facts/dsip",
            "mainEntity": [
                {
                    "@type": "Question",
                    "name": "What is the chemical structure of DSIP?",
                    "acceptedAnswer": {
                        "@type": "Answer",
                        "text": "DSIP is a nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, molecular weight ~850 daltons, and an amphipathic structure. Lab-grade material is produced by chemical synthesis."
                    }
                },
                {
                    "@type": "Question",
                    "name": "Is DSIP FDA-approved or banned in sport?",
                    "acceptedAnswer": {
                        "@type": "Answer",
                        "text": "DSIP is not FDA-approved for any condition. It is not named on the WADA Prohibited List but may fall under class S0 (Non-Approved Substances). Athletes subject to testing should consult their anti-doping authority."
                    }
                },
                {
                    "@type": "Question",
                    "name": "How do researchers reconstitute lyophilized DSIP for laboratory use?",
                    "acceptedAnswer": {
                        "@type": "Answer",
                        "text": "Add a measured volume of bacteriostatic water to the lyophilized vial, then calculate working concentration by dividing mg of peptide by mL of water added (e.g., 5 mg ÷ 2.5 mL = 2 mg/mL)."
                    }
                }
            ]
        }
    ],
    "dates": {
        "published": "2026-08-15",
        "modified": "2026-10-16"
    }
}