# Kisspeptin: Reference Overview and Reconstitution Notes - facts

Canonical page: https://www.preppinpeppers.com/blogs/the-lab/kisspeptin
Type: Lab article

## TL;DR

Kisspeptin: the KISS1-encoded neuropeptide family (kisspeptin-54, -14, -13 and -10) studied in reproductive research. Reference and reconstitution notes.

## Facts Index

| Fact ID | Category | Entity | Attribute | Value | Source | Evidence |
|---|---|---|---|---|---|---|
| kisspeptin:title | identity | Kisspeptin: Reference Overview and Reconstitution Notes | title | Kisspeptin: Reference Overview and Reconstitution Notes | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:published | identity | Kisspeptin: Reference Overview and Reconstitution Notes | published | 2026-08-15 | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:author | identity | Kisspeptin: Reference Overview and Reconstitution Notes | author | Preppin' Peppers Editorial Team | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:topics | identity | Kisspeptin: Reference Overview and Reconstitution Notes | topics | research, Research-only | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:summary | content | Kisspeptin: Reference Overview and Reconstitution Notes | summary | Kisspeptin: the KISS1-encoded neuropeptide family (kisspeptin-54, -14, -13 and -10) studied in reproductive research. Reference and reconstitution notes. | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-1 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-2 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | Kisspeptin | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-3 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | Kisspeptin | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-4 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-5 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | Research context and categorization | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-6 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | Status | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-7 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | Reconstitution notes (general) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-8 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | Dilution and handling notes (compound-specific) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-9 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | Handling and storage | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-10 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | Related reading | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-11 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | Tools and supplies | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:section-13 | content | Kisspeptin: Reference Overview and Reconstitution Notes | section | What the research community gets wrong about kisspeptin | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/blogs/the-lab/kisspeptin |
| kisspeptin:product-gansulin-metal-peptide-pen | products | Kisspeptin: Reference Overview and Reconstitution Notes | references product | Gansulin Pen · Reusable Click-Dial, 3 ml (1-60 Units) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/products/gansulin-metal-peptide-pen |
| kisspeptin:product-gansulin-3ml-cartridge | products | Kisspeptin: Reference Overview and Reconstitution Notes | references product | Gansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.preppinpeppers.com/products/gansulin-3ml-cartridge |
| kisspeptin:source-www-ncbi-nlm-nih-gov | source | Kisspeptin: Reference Overview and Reconstitution Notes | cites | NCBI Gene ID 3814: KISS1 (KiSS-1 metastasis suppressor), Homo sapiens - www.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.ncbi.nlm.nih.gov/gene/3814 |
| kisspeptin:source-www-uniprot-org | source | Kisspeptin: Reference Overview and Reconstitution Notes | cites | UniProtKB Q15726: Metastasis-suppressor KiSS-1 (KISS1, Homo sapiens), UniProt release 2026-03 - www.uniprot.org | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://www.uniprot.org/uniprotkb/Q15726/entry |
| kisspeptin:source-pubchem-ncbi-nlm-nih-gov | source | Kisspeptin: Reference Overview and Reconstitution Notes | cites | NCBI PubChem CID 25240297: Kisspeptin-10 (C63H83N17O14) - pubchem.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://pubchem.ncbi.nlm.nih.gov/compound/25240297 |
| kisspeptin:source-pubmed-ncbi-nlm-nih-gov | source | Kisspeptin: Reference Overview and Reconstitution Notes | cites | Meczekalski et al., Curr Opin Pharmacol 2022: Stress, kisspeptin, and functional hypothalamic amenorrhea - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://pubmed.ncbi.nlm.nih.gov/36103784/ |
| kisspeptin:source-pubmed-ncbi-nlm-nih-gov-2 | source | Kisspeptin: Reference Overview and Reconstitution Notes | cites | Grattan and Szawka, Semin Reprod Med 2019: Kisspeptin and Prolactin - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://pubmed.ncbi.nlm.nih.gov/31847029/ |
| kisspeptin:source-pubmed-ncbi-nlm-nih-gov-3 | source | Kisspeptin: Reference Overview and Reconstitution Notes | cites | Mills et al., Semin Reprod Med 2019: Kisspeptin as a Behavioral Hormone - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) | https://pubmed.ncbi.nlm.nih.gov/31847025/ |

## FAQ

### What is kisspeptin and how does it work in laboratory research?

Kisspeptin is a neuropeptide family encoded by the KISS1 gene that binds the GPR54 receptor (KISS1R). Researchers study its role as an upstream trigger for GnRH along the HPG axis; isoforms include kisspeptin-54, -14, -13, and -10.

### What is the regulatory and doping status of kisspeptin?

Kisspeptin is research-only and is not approved by any regulator, including the FDA. A 2024 FDA advisory committee voted against adding kisspeptin-10 to a compounding substances list. It is also prohibited under WADA S2 (Peptide Hormones) for male athletes.

### How do you calculate concentration when reconstituting a peptide vial?

Divide the vial's milligram amount by the volume of bacteriostatic water added in milliliters. For example, 10 mg dissolved in 2 mL yields 5 mg/mL. A peptide calculator can then convert that figure into smaller working units.

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