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            "q": "Why are employers restricting GLP-1 drug coverage?",
            "a": "GLP-1 medications like semaglutide cost $1,000–$1,300/month. Employers limit access via prior authorization, step therapy, weight-program mandates, and outright plan exclusions to control rising health-plan costs."
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            "q": "What structural modifications give semaglutide a long half-life?",
            "a": "Semaglutide carries a fatty acid chain at one residue plus two amino acid substitutions. Together these extend its half-life to ~165 hours versus 1–2 minutes for native GLP-1, directly affecting solution stability and reconstitution behavior."
        },
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            "q": "How does tirzepatide differ mechanistically from semaglutide?",
            "a": "Tirzepatide is a dual agonist activating both the GLP-1 and GIP receptors simultaneously; semaglutide targets only the GLP-1 receptor, making the two structurally modified peptides mechanistically distinct research tools."
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