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AOD-9604: Reference Overview and Reconstitution Notes

Machine-readable facts for this Lab article. The full page is https://www.preppinpeppers.com/blogs/the-lab/aod-9604.

TL;DR

AOD-9604 is a synthetic fragment of human growth hormone (positions 176-191) studied in metabolic research. Not approved by any major regulator. Lab notes.

Facts Index

Fact IDCategoryEntityAttributeValueSource
aod-9604:titleidentityAOD-9604: Reference Overview and Reconstitution NotestitleAOD-9604: Reference Overview and Reconstitution NotesLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:publishedidentityAOD-9604: Reference Overview and Reconstitution Notespublished2026-08-15Lab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:authoridentityAOD-9604: Reference Overview and Reconstitution NotesauthorPreppin' Peppers Editorial TeamLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:topicsidentityAOD-9604: Reference Overview and Reconstitution Notestopicsresearch, Research-onlyLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:summarycontentAOD-9604: Reference Overview and Reconstitution NotessummaryAOD-9604 is a synthetic fragment of human growth hormone (positions 176-191) studied in metabolic research. Not approved by any major regulator. Lab notes.Lab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:section-1contentAOD-9604: Reference Overview and Reconstitution NotessectionWhat it isLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:section-2contentAOD-9604: Reference Overview and Reconstitution NotessectionAOD-9604Lab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:section-3contentAOD-9604: Reference Overview and Reconstitution NotessectionWhat it isLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:section-4contentAOD-9604: Reference Overview and Reconstitution NotessectionResearch context and categorizationLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:section-5contentAOD-9604: Reference Overview and Reconstitution NotessectionStatusLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:section-6contentAOD-9604: Reference Overview and Reconstitution NotessectionReconstitution notes (general)Lab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:section-7contentAOD-9604: Reference Overview and Reconstitution NotessectionDilution and handling notes (compound-specific)Lab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:section-8contentAOD-9604: Reference Overview and Reconstitution NotessectionHandling and storageLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:section-9contentAOD-9604: Reference Overview and Reconstitution NotessectionRelated readingLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:section-10contentAOD-9604: Reference Overview and Reconstitution NotessectionTools and suppliesLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:section-12contentAOD-9604: Reference Overview and Reconstitution NotessectionWhat the research community gets wrong about AOD-9604Lab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:product-gansulin-metal-peptide-penproductsAOD-9604: Reference Overview and Reconstitution Notesreferences productGansulin Pen ยท Reusable Click-Dial, 3 ml (1-60 Units)Lab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:product-gansulin-3ml-cartridgeproductsAOD-9604: Reference Overview and Reconstitution Notesreferences productGansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack)Lab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:source-pubchem-ncbi-nlm-nih-govsourceAOD-9604: Reference Overview and Reconstitution NotescitesNCBI PubChem CID 71300630: Aod-9604 (C78H123N23O23S2) - pubchem.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:source-pubmed-ncbi-nlm-nih-govsourceAOD-9604: Reference Overview and Reconstitution NotescitesWilding, Curr Opin Investig Drugs 2004: AOD-9604 Metabolic - pubmed.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:source-www-annclinlabsci-orgsourceAOD-9604: Reference Overview and Reconstitution NotescitesKwon DR, Park GY. Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model. Ann Clin Lab Sci. 2015;45(4):426-432 - www.annclinlabsci.orgLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:source-pubmed-ncbi-nlm-nih-gov-2sourceAOD-9604: Reference Overview and Reconstitution NotescitesNg et al., Horm Res 2000: Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone - pubmed.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)
aod-9604:source-pubmed-ncbi-nlm-nih-gov-3sourceAOD-9604: Reference Overview and Reconstitution NotescitesCox et al., Drug Test Anal 2015: Detection and in vitro metabolism of AOD9604 - pubmed.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/aod-9604) (evidence)

FAQ

Does AOD-9604 bind the growth hormone receptor or raise IGF-1?
Published studies report AOD-9604 does not bind the growth hormone receptor and does not elevate IGF-1, distinguishing its investigated mechanism from full growth-hormone activity in preclinical models.
What is the regulatory and anti-doping status of AOD-9604?
AOD-9604 is not approved as a drug by any major agency. WADA lists it under S0 (non-approved substances). A GRAS determination covers oral food-ingredient use only and does not extend to injectable preparations.
What research models have been used to study AOD-9604?
Studies have employed animal models, cell-culture systems, and collagenase-induced osteoarthritis models. A formal human clinical program was conducted but did not result in drug approval; all findings remain investigational.