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ARA-290: Reference Overview and Reconstitution Notes
Machine-readable facts for this Lab article. The full page is https://www.preppinpeppers.com/blogs/the-lab/ara-290.
TL;DR
ARA-290 (cibinetide) is an 11-amino-acid synthetic peptide studied in tissue repair and inflammation research. Not approved by any regulator. Lab notes.
Facts Index
| Fact ID | Category | Entity | Attribute | Value | Source |
|---|---|---|---|---|---|
| ara-290:title | identity | ARA-290: Reference Overview and Reconstitution Notes | title | ARA-290: Reference Overview and Reconstitution Notes | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:published | identity | ARA-290: Reference Overview and Reconstitution Notes | published | 2026-08-15 | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:author | identity | ARA-290: Reference Overview and Reconstitution Notes | author | Preppin' Peppers Editorial Team | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:topics | identity | ARA-290: Reference Overview and Reconstitution Notes | topics | Investigational, research | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:summary | content | ARA-290: Reference Overview and Reconstitution Notes | summary | ARA-290 (cibinetide) is an 11-amino-acid synthetic peptide studied in tissue repair and inflammation research. Not approved by any regulator. Lab notes. | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:section-1 | content | ARA-290: Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:section-2 | content | ARA-290: Reference Overview and Reconstitution Notes | section | ARA-290 | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:section-3 | content | ARA-290: Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:section-4 | content | ARA-290: Reference Overview and Reconstitution Notes | section | Research context and categorization | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:section-5 | content | ARA-290: Reference Overview and Reconstitution Notes | section | Status | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:section-6 | content | ARA-290: Reference Overview and Reconstitution Notes | section | Reconstitution notes (general) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:section-7 | content | ARA-290: Reference Overview and Reconstitution Notes | section | Dilution and handling notes (compound-specific) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:section-8 | content | ARA-290: Reference Overview and Reconstitution Notes | section | Handling and storage | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:section-9 | content | ARA-290: Reference Overview and Reconstitution Notes | section | Related reading | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:section-10 | content | ARA-290: Reference Overview and Reconstitution Notes | section | Tools and supplies | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:section-12 | content | ARA-290: Reference Overview and Reconstitution Notes | section | What the research community gets wrong about ARA-290 | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:product-gansulin-metal-peptide-pen | products | ARA-290: Reference Overview and Reconstitution Notes | references product | Gansulin Pen ยท Reusable Click-Dial, 3 ml (1-60 Units) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:product-gansulin-3ml-cartridge | products | ARA-290: Reference Overview and Reconstitution Notes | references product | Gansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:source-pubchem-ncbi-nlm-nih-gov | source | ARA-290: Reference Overview and Reconstitution Notes | cites | NCBI PubChem CID 91810664: Cibinetide (C51H84N16O21) - pubchem.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:source-pubmed-ncbi-nlm-nih-gov | source | ARA-290: Reference Overview and Reconstitution Notes | cites | Heij et al., Mol Med 2012: Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy: a randomized, double-blind pilot study - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:source-pubmed-ncbi-nlm-nih-gov-2 | source | ARA-290: Reference Overview and Reconstitution Notes | cites | van Velzen et al., Expert Opin Investig Drugs 2014: ARA 290 for treatment of small fiber neuropathy in sarcoidosis - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:source-pubmed-ncbi-nlm-nih-gov-3 | source | ARA-290: Reference Overview and Reconstitution Notes | cites | Chen et al., J Neuroimmunol 2014: Therapeutic effects of nonerythropoietic erythropoietin analog ARA290 in experimental autoimmune encephalomyelitis rat - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:source-pubmed-ncbi-nlm-nih-gov-4 | source | ARA-290: Reference Overview and Reconstitution Notes | cites | Rendell, Expert Opin Investig Drugs 2021: The time to develop treatments for diabetic neuropathy - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
| ara-290:source-clinicaltrials-gov | source | ARA-290: Reference Overview and Reconstitution Notes | cites | ClinicalTrials.gov NCT02039687 (Phase 2, completed, first posted 2014-01-20): Study of Efficacy of ARA 290 on Corneal Nerve Fiber Density and Neuropathic Symptoms of Subjects With Sarcoidosis - clinicaltrials.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/ara-290) (evidence) |
FAQ
- What is ARA-290 and how does it work in research?
- ARA-290 is a synthetic 11-amino-acid peptide derived from EPO that is studied for its ability to bind the innate repair receptor (IRR), signaling tissue-protective and anti-inflammatory pathways in laboratory models.
- What is the regulatory status of ARA-290?
- No. ARA-290 is not approved by any regulator for any use. It holds Orphan Drug and Fast Track designations and reached Phase 2 trials for sarcoidosis-related neuropathic pain but remains strictly a research-only compound, not a licensed product.
- How is lyophilized ARA-290 reconstituted at the lab bench?
- The freeze-dried powder is dissolved in bacteriostatic water; the resulting concentration equals the peptide mass in milligrams divided by the volume of solvent added. No dosing guidance is implied or given.