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DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes
Machine-readable facts for this Lab article. The full page is https://www.preppinpeppers.com/blogs/the-lab/dsip.
TL;DR
DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nine-amino-acid neuropeptide studied in sleep and neuroendocrine research. Not FDA-approved.
Facts Index
| Fact ID | Category | Entity | Attribute | Value | Source |
|---|---|---|---|---|---|
| dsip:title | identity | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | title | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:published | identity | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | published | 2026-08-15 | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:author | identity | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | author | Preppin' Peppers Editorial Team | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:topics | identity | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | topics | research, Research-only | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:summary | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | summary | DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nine-amino-acid neuropeptide studied in sleep and neuroendocrine research. Not FDA-approved. | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:section-1 | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:section-2 | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | section | DSIP (Delta Sleep-Inducing Peptide) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:section-3 | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:section-4 | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | section | Research context and categorization | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:section-5 | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | section | Status | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:section-6 | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | section | Reconstitution notes (general) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:section-7 | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | section | Dilution and handling notes (compound-specific) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:section-8 | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | section | Handling and storage | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:section-9 | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | section | Related reading | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:section-10 | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | section | Tools and supplies | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:section-12 | content | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | section | What the research community gets wrong about DSIP handling | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:product-gansulin-metal-peptide-pen | products | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | references product | Gansulin Pen · Reusable Click-Dial, 3 ml (1-60 Units) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:product-gansulin-3ml-cartridge | products | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | references product | Gansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:source-pubmed-ncbi-nlm-nih-gov | source | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | cites | Graf and Kastin, Neurosci Biobehav Rev 1984: Delta-sleep-inducing peptide (DSIP): a review - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:source-pubmed-ncbi-nlm-nih-gov-2 | source | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | cites | Schoenenberger et al., Pflugers Arch 1978: The delta EEG (sleep)-inducing peptide (DSIP). XI. Amino-acid analysis, sequence, synthesis and activity of the nonapeptide - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:source-pubchem-ncbi-nlm-nih-gov | source | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | cites | NCBI PubChem CID 68816: Delta Sleep-Inducing Peptide (C35H48N10O15) - pubchem.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:source-pubmed-ncbi-nlm-nih-gov-3 | source | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | cites | Pollard and Pomfrett, Eur J Anaesthesiol 2001: Delta sleep-inducing peptide - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:source-pubmed-ncbi-nlm-nih-gov-4 | source | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | cites | Graf et al., Pharmacol Biochem Behav 1984: DSIP occurs in free form in mammalian plasma, human CSF and urine - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
| dsip:source-pubmed-ncbi-nlm-nih-gov-5 | source | DSIP (Delta Sleep-Inducing Peptide): Reference Overview and Reconstitution Notes | cites | Gimble et al., Obes Rev 2009: Delta sleep-inducing peptide and glucocorticoid-induced leucine zipper: potential links between circadian mechanisms and obesity? - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/dsip) (evidence) |
FAQ
- What is the chemical structure of DSIP?
- DSIP is a nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, molecular weight ~850 daltons, and an amphipathic structure. Lab-grade material is produced by chemical synthesis.
- Is DSIP FDA-approved or banned in sport?
- DSIP is not FDA-approved for any condition. It is not named on the WADA Prohibited List but may fall under class S0 (Non-Approved Substances). Athletes subject to testing should consult their anti-doping authority.
- How do researchers reconstitute lyophilized DSIP for laboratory use?
- Add a measured volume of bacteriostatic water to the lyophilized vial, then calculate working concentration by dividing mg of peptide by mL of water added (e.g., 5 mg ÷ 2.5 mL = 2 mg/mL).