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EPO: Reference Overview and Reconstitution Notes

Machine-readable facts for this Lab article. The full page is https://www.preppinpeppers.com/blogs/the-lab/epo.

TL;DR

EPO (erythropoietin) is a glycoprotein hormone and hematopoietic growth factor that signals red blood cell production. Prohibited in sport by WADA. Lab notes.

Facts Index

Fact IDCategoryEntityAttributeValueSource
epo:titleidentityEPO: Reference Overview and Reconstitution NotestitleEPO: Reference Overview and Reconstitution NotesLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:publishedidentityEPO: Reference Overview and Reconstitution Notespublished2026-08-15Lab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:authoridentityEPO: Reference Overview and Reconstitution NotesauthorPreppin' Peppers Editorial TeamLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:topicsidentityEPO: Reference Overview and Reconstitution NotestopicsFDA-approved or specific-use, researchLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:summarycontentEPO: Reference Overview and Reconstitution NotessummaryEPO (erythropoietin) is a glycoprotein hormone and hematopoietic growth factor that signals red blood cell production. Prohibited in sport by WADA. Lab notes.Lab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:section-1contentEPO: Reference Overview and Reconstitution NotessectionEPOLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:section-2contentEPO: Reference Overview and Reconstitution NotessectionWhat it isLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:section-3contentEPO: Reference Overview and Reconstitution NotessectionResearch context and categorizationLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:section-4contentEPO: Reference Overview and Reconstitution NotessectionStatusLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:section-5contentEPO: Reference Overview and Reconstitution NotessectionReconstitution notes (general)Lab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:section-6contentEPO: Reference Overview and Reconstitution NotessectionDilution and handling notes (compound-specific)Lab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:section-7contentEPO: Reference Overview and Reconstitution NotessectionHandling and storageLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:section-8contentEPO: Reference Overview and Reconstitution NotessectionRelated readingLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:section-9contentEPO: Reference Overview and Reconstitution NotessectionTools and suppliesLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:section-11contentEPO: Reference Overview and Reconstitution NotessectionWhat the research community gets wrong about EPO handlingLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:product-gansulin-metal-peptide-penproductsEPO: Reference Overview and Reconstitution Notesreferences productGansulin Pen ยท Reusable Click-Dial, 3 ml (1-60 Units)Lab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:product-gansulin-3ml-cartridgeproductsEPO: Reference Overview and Reconstitution Notesreferences productGansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack)Lab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:source-dailymed-nlm-nih-govsourceEPO: Reference Overview and Reconstitution NotescitesEPOGEN (epoetin alfa) prescribing label, FDA/DailyMed (human albumin as a formulation component; store at 2 to 8 degrees C; do not shake or freeze; protect from light) - dailymed.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:source-www-uniprot-orgsourceEPO: Reference Overview and Reconstitution NotescitesUniProtKB P01588: Erythropoietin (EPO, Homo sapiens), UniProt release 2026-03 - www.uniprot.orgLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:source-pubmed-ncbi-nlm-nih-govsourceEPO: Reference Overview and Reconstitution NotescitesNaughton et al., Am J Health Syst Pharm 2003: Stability of multidose, preserved formulation epoetin alfa in syringes for three and six weeks - pubmed.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:source-pubmed-ncbi-nlm-nih-gov-2sourceEPO: Reference Overview and Reconstitution NotescitesSpivak, Annu Rev Med 1993: Recombinant erythropoietin - pubmed.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:source-pubmed-ncbi-nlm-nih-gov-3sourceEPO: Reference Overview and Reconstitution NotescitesDelanghe et al., Am J Hematol 2008: Testing for recombinant erythropoietin - pubmed.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)
epo:source-pubmed-ncbi-nlm-nih-gov-4sourceEPO: Reference Overview and Reconstitution NotescitesJelkmann, Front Horm Res 2016: Erythropoietin - pubmed.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/epo) (evidence)

FAQ

What is EPO and how does it work?
EPO (erythropoietin) is a glycoprotein hormone produced mainly by the kidneys that signals bone marrow to increase red blood cell production; recombinant versions (e.g., epoetin alfa) mimic this signaling action.
What is the regulatory status of the EPO products listed here?
No. Recombinant human EPO has not been evaluated or approved by any regulatory authority, including the FDA, and it is not a licensed product for human or veterinary use. It is intended for research purposes only, and any medical use of EPO falls outside the scope of this article.
How is concentration calculated when reconstituting a lyophilized EPO vial?
Divide the total amount in the vial by the volume of solvent added. For example, adding 1 mL to a vial yields a concentration equal to the full vial content per milliliter.