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HCG: Reference Overview and Reconstitution Notes
Machine-readable facts for this Lab article. The full page is https://www.preppinpeppers.com/blogs/the-lab/hcg.
TL;DR
HCG (human chorionic gonadotropin) is a protein-based gonadotropin hormone studied in reproductive and endocrine research. Not approved by any regulator.
Facts Index
| Fact ID | Category | Entity | Attribute | Value | Source |
|---|---|---|---|---|---|
| hcg:title | identity | HCG: Reference Overview and Reconstitution Notes | title | HCG: Reference Overview and Reconstitution Notes | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:published | identity | HCG: Reference Overview and Reconstitution Notes | published | 2026-08-15 | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:author | identity | HCG: Reference Overview and Reconstitution Notes | author | Preppin' Peppers Editorial Team | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:topics | identity | HCG: Reference Overview and Reconstitution Notes | topics | FDA-approved or specific-use, research | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:summary | content | HCG: Reference Overview and Reconstitution Notes | summary | HCG (human chorionic gonadotropin) is a protein-based gonadotropin hormone studied in reproductive and endocrine research. Not approved by any regulator. | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:section-1 | content | HCG: Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:section-2 | content | HCG: Reference Overview and Reconstitution Notes | section | HCG | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:section-3 | content | HCG: Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:section-4 | content | HCG: Reference Overview and Reconstitution Notes | section | Research context and categorization | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:section-5 | content | HCG: Reference Overview and Reconstitution Notes | section | Status | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:section-6 | content | HCG: Reference Overview and Reconstitution Notes | section | Reconstitution notes (general) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:section-7 | content | HCG: Reference Overview and Reconstitution Notes | section | Dilution and handling notes (compound-specific) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:section-8 | content | HCG: Reference Overview and Reconstitution Notes | section | Handling and storage | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:section-9 | content | HCG: Reference Overview and Reconstitution Notes | section | Related reading | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:section-10 | content | HCG: Reference Overview and Reconstitution Notes | section | Tools and supplies | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:section-12 | content | HCG: Reference Overview and Reconstitution Notes | section | What the research community gets wrong about HCG | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:product-gansulin-metal-peptide-pen | products | HCG: Reference Overview and Reconstitution Notes | references product | Gansulin Pen · Reusable Click-Dial, 3 ml (1-60 Units) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:product-gansulin-3ml-cartridge | products | HCG: Reference Overview and Reconstitution Notes | references product | Gansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:source-pmc-ncbi-nlm-nih-gov | source | HCG: Reference Overview and Reconstitution Notes | cites | Cole, Reprod Biol Endocrinol 2009: New discoveries on the biology and detection of human chorionic gonadotropin - pmc.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:source-pmc-ncbi-nlm-nih-gov-2 | source | HCG: Reference Overview and Reconstitution Notes | cites | Broksø Kyhl et al., Clin Transl Sci 2021: First-in-human trial assessing the pharmacokinetic-pharmacodynamic profile of a novel recombinant human chorionic gonadotropin in healthy women and men of reproductive age - pmc.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:source-www-prnewswire-com | source | HCG: Reference Overview and Reconstitution Notes | cites | FDA Consumer Health Information: HCG Diet Products Are Illegal (FDA notice, 2011) - www.prnewswire.com | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:source-pmc-ncbi-nlm-nih-gov-3 | source | HCG: Reference Overview and Reconstitution Notes | cites | Heidegger and Jeschke, Int J Mol Sci 2018: Human Chorionic Gonadotropin (hCG)-An Endocrine, Regulator of Gestation and Cancer - pmc.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:source-www-uniprot-org | source | HCG: Reference Overview and Reconstitution Notes | cites | UniProtKB/Swiss-Prot P0DN86: Choriogonadotropin subunit beta 3 (CGB3, Homo sapiens), UniProt release 2026-03 - www.uniprot.org | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
| hcg:source-clinicaltrials-gov | source | HCG: Reference Overview and Reconstitution Notes | cites | ClinicalTrials.gov NCT01786252 (Phase 4, completed, first posted 2013-02-07): Effect of hCG on Receptivity of the Human Endometrium - clinicaltrials.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/hcg) (evidence) |
FAQ
- What is the chemical structure of HCG?
- HCG is a glycoprotein hormone composed of two subunits: an alpha subunit structurally similar to LH and FSH, and a unique beta subunit that defines HCG's distinct receptor-binding identity.
- How is HCG lyophilized powder reconstituted for laboratory use?
- Add bacteriostatic water to the vial and swirl gently — never shake. Divide total IU by water volume added to find concentration (e.g., 5,000 IU ÷ 2 mL = 2,500 IU/mL). Refrigerate at 2–8 °C after mixing.
- Is HCG listed on the WADA Prohibited List?
- Yes. WADA classifies chorionic gonadotropin (CG) under S2 (peptide hormones, growth factors, related substances and mimetics) and prohibits it in males at all times, both in and out of competition.