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IGF-1 LR3: Reference Overview and Reconstitution Notes
Machine-readable facts for this Lab article. The full page is https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3.
TL;DR
IGF-1 LR3 is a lab-made, long-acting analog of insulin-like growth factor 1, supplied only as a research reference material. Not FDA-approved. Lab notes.
Facts Index
| Fact ID | Category | Entity | Attribute | Value | Source |
|---|---|---|---|---|---|
| igf-1-lr3:title | identity | IGF-1 LR3: Reference Overview and Reconstitution Notes | title | IGF-1 LR3: Reference Overview and Reconstitution Notes | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:published | identity | IGF-1 LR3: Reference Overview and Reconstitution Notes | published | 2026-08-15 | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:author | identity | IGF-1 LR3: Reference Overview and Reconstitution Notes | author | Preppin' Peppers Editorial Team | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:topics | identity | IGF-1 LR3: Reference Overview and Reconstitution Notes | topics | research, Research-only | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:summary | content | IGF-1 LR3: Reference Overview and Reconstitution Notes | summary | IGF-1 LR3 is a lab-made, long-acting analog of insulin-like growth factor 1, supplied only as a research reference material. Not FDA-approved. Lab notes. | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:section-1 | content | IGF-1 LR3: Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:section-2 | content | IGF-1 LR3: Reference Overview and Reconstitution Notes | section | What it is | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:section-3 | content | IGF-1 LR3: Reference Overview and Reconstitution Notes | section | Research context and categorization | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:section-4 | content | IGF-1 LR3: Reference Overview and Reconstitution Notes | section | Status | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:section-5 | content | IGF-1 LR3: Reference Overview and Reconstitution Notes | section | Reconstitution notes (general) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:section-6 | content | IGF-1 LR3: Reference Overview and Reconstitution Notes | section | Dilution and handling notes (compound-specific) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:section-7 | content | IGF-1 LR3: Reference Overview and Reconstitution Notes | section | Handling and storage | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:section-8 | content | IGF-1 LR3: Reference Overview and Reconstitution Notes | section | Related reading | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:section-9 | content | IGF-1 LR3: Reference Overview and Reconstitution Notes | section | Tools and supplies | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:section-11 | content | IGF-1 LR3: Reference Overview and Reconstitution Notes | section | What the research community gets wrong about IGF-1 LR3 handling | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:product-gansulin-metal-peptide-pen | products | IGF-1 LR3: Reference Overview and Reconstitution Notes | references product | Gansulin Pen · Reusable Click-Dial, 3 ml (1-60 Units) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:product-gansulin-3ml-cartridge | products | IGF-1 LR3: Reference Overview and Reconstitution Notes | references product | Gansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack) | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:source-www-uniprot-org | source | IGF-1 LR3: Reference Overview and Reconstitution Notes | cites | UniProtKB P05019: Insulin-like growth factor 1 (IGF1, Homo sapiens), UniProt release 2026-03 - www.uniprot.org | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:source-pubmed-ncbi-nlm-nih-gov | source | IGF-1 LR3: Reference Overview and Reconstitution Notes | cites | Dunaiski et al., J Endocrinol 1997: Long [R3] insulin-like growth factor-I reduces growth, plasma growth hormone, IGF binding protein-3 and endogenous IGF-I concentrations in pigs - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:source-pubmed-ncbi-nlm-nih-gov-2 | source | IGF-1 LR3: Reference Overview and Reconstitution Notes | cites | Pell et al., Prog Growth Factor Res 1995: Further characterisation of an IGF-I enhancing antibody: actions on IGF-I-induced hypoglycaemia and interaction with the analogue LR3IGF-I - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
| igf-1-lr3:source-pubmed-ncbi-nlm-nih-gov-3 | source | IGF-1 LR3: Reference Overview and Reconstitution Notes | cites | Dunshea et al., Br J Nutr 2002: Insulin-like growth factor-I and analogues increase growth in artificially-reared neonatal pigs - pubmed.ncbi.nlm.nih.gov | Lab article (https://www.preppinpeppers.com/blogs/the-lab/igf-1-lr3) (evidence) |
FAQ
- What makes IGF-1 LR3 different from natural IGF-1?
- Two structural changes — an arginine substitution at position 3 and a 13-amino-acid N-terminal extension — reduce IGF-binding-protein affinity, extending the compound's active window in cell and tissue lab studies.
- How do you reconstitute IGF-1 LR3 for laboratory use?
- Add bacteriostatic water to the lyophilized powder; divide the vial's mg content by the mL of diluent added to get concentration (e.g., 1 mg ÷ 1 mL = 1 mg/mL). Use a peptide calculator to confirm volumes before use.
- What is the regulatory and sport status of IGF-1 LR3?
- It is a research chemical for in-vitro use only, is not FDA-approved, and is not approved by any regulator. It is prohibited at all times under WADA Prohibited List class S2. Check applicable local regulations.