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Kisspeptin: Reference Overview and Reconstitution Notes

Machine-readable facts for this Lab article. The full page is https://www.preppinpeppers.com/blogs/the-lab/kisspeptin.

TL;DR

Kisspeptin: the KISS1-encoded neuropeptide family (kisspeptin-54, -14, -13 and -10) studied in reproductive research. Reference and reconstitution notes.

Facts Index

Fact IDCategoryEntityAttributeValueSource
kisspeptin:titleidentityKisspeptin: Reference Overview and Reconstitution NotestitleKisspeptin: Reference Overview and Reconstitution NotesLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:publishedidentityKisspeptin: Reference Overview and Reconstitution Notespublished2026-08-15Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:authoridentityKisspeptin: Reference Overview and Reconstitution NotesauthorPreppin' Peppers Editorial TeamLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:topicsidentityKisspeptin: Reference Overview and Reconstitution Notestopicsresearch, Research-onlyLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:summarycontentKisspeptin: Reference Overview and Reconstitution NotessummaryKisspeptin: the KISS1-encoded neuropeptide family (kisspeptin-54, -14, -13 and -10) studied in reproductive research. Reference and reconstitution notes.Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-1contentKisspeptin: Reference Overview and Reconstitution NotessectionWhat it isLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-2contentKisspeptin: Reference Overview and Reconstitution NotessectionKisspeptinLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-3contentKisspeptin: Reference Overview and Reconstitution NotessectionKisspeptinLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-4contentKisspeptin: Reference Overview and Reconstitution NotessectionWhat it isLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-5contentKisspeptin: Reference Overview and Reconstitution NotessectionResearch context and categorizationLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-6contentKisspeptin: Reference Overview and Reconstitution NotessectionStatusLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-7contentKisspeptin: Reference Overview and Reconstitution NotessectionReconstitution notes (general)Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-8contentKisspeptin: Reference Overview and Reconstitution NotessectionDilution and handling notes (compound-specific)Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-9contentKisspeptin: Reference Overview and Reconstitution NotessectionHandling and storageLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-10contentKisspeptin: Reference Overview and Reconstitution NotessectionRelated readingLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-11contentKisspeptin: Reference Overview and Reconstitution NotessectionTools and suppliesLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:section-13contentKisspeptin: Reference Overview and Reconstitution NotessectionWhat the research community gets wrong about kisspeptinLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:product-gansulin-metal-peptide-penproductsKisspeptin: Reference Overview and Reconstitution Notesreferences productGansulin Pen ยท Reusable Click-Dial, 3 ml (1-60 Units)Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:product-gansulin-3ml-cartridgeproductsKisspeptin: Reference Overview and Reconstitution Notesreferences productGansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack)Lab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:source-www-ncbi-nlm-nih-govsourceKisspeptin: Reference Overview and Reconstitution NotescitesNCBI Gene ID 3814: KISS1 (KiSS-1 metastasis suppressor), Homo sapiens - www.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:source-www-uniprot-orgsourceKisspeptin: Reference Overview and Reconstitution NotescitesUniProtKB Q15726: Metastasis-suppressor KiSS-1 (KISS1, Homo sapiens), UniProt release 2026-03 - www.uniprot.orgLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:source-pubchem-ncbi-nlm-nih-govsourceKisspeptin: Reference Overview and Reconstitution NotescitesNCBI PubChem CID 25240297: Kisspeptin-10 (C63H83N17O14) - pubchem.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:source-pubmed-ncbi-nlm-nih-govsourceKisspeptin: Reference Overview and Reconstitution NotescitesMeczekalski et al., Curr Opin Pharmacol 2022: Stress, kisspeptin, and functional hypothalamic amenorrhea - pubmed.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:source-pubmed-ncbi-nlm-nih-gov-2sourceKisspeptin: Reference Overview and Reconstitution NotescitesGrattan and Szawka, Semin Reprod Med 2019: Kisspeptin and Prolactin - pubmed.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)
kisspeptin:source-pubmed-ncbi-nlm-nih-gov-3sourceKisspeptin: Reference Overview and Reconstitution NotescitesMills et al., Semin Reprod Med 2019: Kisspeptin as a Behavioral Hormone - pubmed.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/kisspeptin) (evidence)

FAQ

What is kisspeptin and how does it work in laboratory research?
Kisspeptin is a neuropeptide family encoded by the KISS1 gene that binds the GPR54 receptor (KISS1R). Researchers study its role as an upstream trigger for GnRH along the HPG axis; isoforms include kisspeptin-54, -14, -13, and -10.
What is the regulatory and doping status of kisspeptin?
Kisspeptin is research-only and is not approved by any regulator, including the FDA. A 2024 FDA advisory committee voted against adding kisspeptin-10 to a compounding substances list. It is also prohibited under WADA S2 (Peptide Hormones) for male athletes.
How do you calculate concentration when reconstituting a peptide vial?
Divide the vial's milligram amount by the volume of bacteriostatic water added in milliliters. For example, 10 mg dissolved in 2 mL yields 5 mg/mL. A peptide calculator can then convert that figure into smaller working units.