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VK2735: Reference Overview and Reconstitution Notes

Machine-readable facts for this Lab article. The full page is https://www.preppinpeppers.com/blogs/the-lab/vk2735.

TL;DR

VK2735 is an investigational dual GLP-1/GIP receptor agonist peptide from Viking Therapeutics, studied in metabolic research. Not FDA-approved for any use.

Facts Index

Fact IDCategoryEntityAttributeValueSource
vk2735:titleidentityVK2735: Reference Overview and Reconstitution NotestitleVK2735: Reference Overview and Reconstitution NotesLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:publishedidentityVK2735: Reference Overview and Reconstitution Notespublished2026-08-15Lab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:authoridentityVK2735: Reference Overview and Reconstitution NotesauthorPreppin' Peppers Editorial TeamLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:topicsidentityVK2735: Reference Overview and Reconstitution NotestopicsInvestigational, researchLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:summarycontentVK2735: Reference Overview and Reconstitution NotessummaryVK2735 is an investigational dual GLP-1/GIP receptor agonist peptide from Viking Therapeutics, studied in metabolic research. Not FDA-approved for any use.Lab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:section-1contentVK2735: Reference Overview and Reconstitution NotessectionWhat it isLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:section-2contentVK2735: Reference Overview and Reconstitution NotessectionVK2735Lab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:section-3contentVK2735: Reference Overview and Reconstitution NotessectionWhat it isLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:section-4contentVK2735: Reference Overview and Reconstitution NotessectionResearch context and categorizationLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:section-5contentVK2735: Reference Overview and Reconstitution NotessectionStatusLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:section-6contentVK2735: Reference Overview and Reconstitution NotessectionReconstitution notes (general)Lab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:section-7contentVK2735: Reference Overview and Reconstitution NotessectionDilution and handling notes (compound-specific)Lab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:section-8contentVK2735: Reference Overview and Reconstitution NotessectionHandling and storageLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:section-9contentVK2735: Reference Overview and Reconstitution NotessectionRelated readingLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:section-10contentVK2735: Reference Overview and Reconstitution NotessectionTools and suppliesLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:section-12contentVK2735: Reference Overview and Reconstitution NotessectionWhat the research community gets wrong about VK2735Lab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:product-gansulin-metal-peptide-penproductsVK2735: Reference Overview and Reconstitution Notesreferences productGansulin Pen ยท Reusable Click-Dial, 3 ml (1-60 Units)Lab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:product-gansulin-3ml-cartridgeproductsVK2735: Reference Overview and Reconstitution Notesreferences productGansulin-Compatible 3 ml Glass Cartridge for Pens (10-Pack)Lab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:source-pubmed-ncbi-nlm-nih-govsourceVK2735: Reference Overview and Reconstitution NotescitesBays et al., Obesity (Silver Spring) 2026: Weekly Subcutaneous VK2735, a GIP/GLP-1 Receptor Dual Agonist, for Weight Management: Phase 2, Randomized, 13-Week VENTURE Study - pubmed.ncbi.nlm.nih.govLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:source-clinicaltrials-govsourceVK2735: Reference Overview and Reconstitution NotescitesClinicalTrials.gov NCT06828055 (Phase 2, completed, first posted 2025-02-14): VK2735 for Weight Management Phase 2 (Venture Oral Dosing) - clinicaltrials.govLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)
vk2735:source-www-uniprot-orgsourceVK2735: Reference Overview and Reconstitution NotescitesUniProtKB/Swiss-Prot P43220: Glucagon-like peptide 1 receptor (GLP1R, Homo sapiens), UniProt release 2026-03 - www.uniprot.orgLab article (https://www.preppinpeppers.com/blogs/the-lab/vk2735) (evidence)

FAQ

What is VK2735 and how does it work?
VK2735 is a man-made dual GLP-1/GIP receptor agonist peptide that activates both glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptors, similar to tirzepatide, studied for metabolic pathways.
What is the regulatory status of VK2735?
VK2735 is a research-only, investigational compound. As of 2026, it has not been approved by any regulatory authority for any use, and it is currently advancing into Phase 3 clinical trials.
What is peptide reconstitution in research?
Reconstitution is adding bacteriostatic water to lyophilized peptide powder to create a solution for lab research, with concentration determined by the volume of water added.