Prostamax: Reference Overview and Reconstitution Notes

Prostamax

What it is

Prostamax is a synthetic short-chain peptide bioregulator from the Khavinson family, associated with prostate tissue. It is commonly described as a defined-sequence peptide (reported as Lys-Glu-Asp-Pro) that was conceived as a synthetic successor to older bovine prostate extracts such as Prostatilen and Vitaprost.

Research context and categorization

Prostamax is grouped under the Khavinson bioregulator category, a set of short peptides discussed in relation to tissue-specific gene expression and anti-aging or longevity research. Within that family, Prostamax is the entry associated with prostate tissue.

In neutral, research-framed terms, it is studied in the context of preclinical models of age-related prostatic change, and it is commonly discussed in relation to tissue repair, inflammatory signaling in prostate tissue, and epigenetic or chromatin-level regulation of gene expression rather than classical receptor binding. It has also been investigated for questions around glandular and reproductive aging in laboratory settings.

These uses are investigational. Prostamax is not FDA-approved, the bulk of the reported work traces to a single originating institute with limited independent replication, and there are no Western randomized controlled trials of the synthetic sequence. Any effects described in the literature should be treated as unconfirmed and not established benefits.

Status

  • Regulatory status: Research-only / not FDA-approved. Prostamax has not been evaluated or registered as a pharmaceutical for human or veterinary use by the FDA, EMA, or comparable authorities.
  • Sport status: Not specifically listed on the WADA Prohibited List. Prostamax is not named on the List, and as a short prostate-associated bioregulator it does not fall within the named growth-factor or peptide-hormone entries (for example the S2 growth hormone secretagogues, GHRPs, or growth factors that affect muscle, tendon, or ligament). Note that WADA can treat an unlisted substance with similar structure or biological effect as prohibited, so this reflects that the compound is not explicitly named rather than a formal clearance.

Reconstitution notes (general)

Concentration is calculated as the milligrams of compound in the vial divided by the millilitres of bacteriostatic water added. For example, a 20 mg vial reconstituted with 2 mL of bacteriostatic water yields 10 mg/mL, while the same vial with 4 mL yields 5 mg/mL. You can work the numbers with the calculator at our reconstitution and blend calculators.

Dilution and handling notes (compound-specific)

Prostamax is supplied as a lyophilized (freeze-dried) powder, most often in a 20 mg vial, and is reconstituted before use. A common approach is to add roughly 2 to 4 mL of bacteriostatic water per 20 mg vial, which places the working concentration in a convenient range and keeps the solution dilute. The higher water volumes are generally chosen to make small-volume measurements easier to draw accurately rather than for any chemical reason. Bacteriostatic water is the standard diluent because its benzyl alcohol content lets a vial be accessed more than once while limiting microbial growth.

As a very small, charged, hydrophilic tetrapeptide (molecular weight around 487 Da, formula C20H33N5O9), Prostamax dissolves readily in sterile or bacteriostatic water and typically forms a clear, colorless solution without heat or aggressive mixing. Gelling, clouding, or persistent precipitation are not typical problems the way they can be with larger or more hydrophobic peptides, so it does not usually require the high-dilution workarounds those compounds sometimes need. It has limited solubility in non-polar organic solvents, so aqueous diluents are the practical choice.

Practical handling quirks are mechanical rather than chemical. Add the water slowly, aiming the stream down the inside wall of the vial rather than directly onto the powder, which reduces foaming, and mix by gentle swirling or rolling rather than shaking hard, since vigorous agitation can foam the solution. The peptide is reported to be light sensitive, so keep it shielded from direct light during preparation and storage. Let the sealed vial and the water reach room temperature first, since cold water can cause transient cloudiness or condensation. A correctly reconstituted solution should look clear and colorless.

Handling and storage

Store the reconstituted vial refrigerated at 2 to 8 degrees Celsius and keep it out of light. Wipe the rubber stopper with an alcohol swab before each puncture, and label the vial with the date it was mixed so you can track its age. Observe the general working window of about four weeks under refrigeration for a bacteriostatic-water solution, and avoid freeze-thaw cycles. Discard anything that turns cloudy or discolored, or that shows visible floaters or particulates.

Related reading

Tools and supplies

For laboratory and research reference only. Educational content, not medical, dosing, injection, or therapeutic guidance, and not intended for human or animal use. Any research uses described are investigational and not confirmed or approved benefits. Confirm anything involving health with a licensed professional. References linked above.