BPC-157
What it is
BPC-157, short for Body Protection Compound 157, is a synthetic pentadecapeptide, meaning a chain of 15 amino acids. Its sequence is a partial sequence derived from a protein reported in human gastric juice, and the compound is produced by laboratory synthesis rather than isolated from tissue.
Research context and categorization
BPC-157 is generally grouped under the healing and tissue-repair category of research peptides. In the published literature it is commonly discussed in relation to soft-tissue models, and it has been investigated for effects on wound, tendon, ligament, muscle, and bone healing, as well as in the context of gastrointestinal injury and inflammatory bowel models. It is also studied in the context of angiogenesis and cytoprotection of internal organs.
It is important to note that the large majority of this work comes from preclinical animal models, primarily small rodents, and often from a limited set of research groups. Human evidence is very limited. These uses are investigational, and the reported effects are not confirmed or approved outcomes in people. Nothing here should be read as an established benefit.
Status
- Regulatory status: Research-only. BPC-157 is not approved by the FDA, or by any other drug regulatory agency, for any human indication. It is not a recognized dietary ingredient, and regulators have flagged it as an unapproved drug substance with outstanding safety and characterization questions.
- Sport status: Prohibited under the WADA Prohibited List. BPC-157 is listed under class S0, Non-Approved Substances, and is prohibited at all times, both in and out of competition. It is also classed as a Specified Substance. Anti-doping bodies have stated that a Therapeutic Use Exemption would not be granted for it, and athletes have been sanctioned over products containing it.
Reconstitution notes (general)
Lyophilized (freeze-dried) peptides are typically reconstituted with bacteriostatic water before measurement. The working concentration is simple to calculate: concentration equals the milligrams of peptide in the vial divided by the millilitres of bacteriostatic water added. For example, 5 mg of powder in 2 mL of water gives 2.5 mg/mL. A reconstitution calculator is available at /pages/tools to check the math for a given vial and fill volume.
Dilution and handling notes (compound-specific)
BPC-157 is supplied as a lyophilized powder, commonly in 5 mg or 10 mg vials, and is reconstituted for laboratory use. Typical water-per-vial choices land in a range of roughly 1 mL to 3 mL per vial, for instance about 2 mL into a 5 mg vial (2.5 mg/mL) or about 3 mL into a 10 mg vial (roughly 3.3 mg/mL). The volume chosen is a matter of the concentration the researcher wants for accurate small-volume measurement, not a fixed rule. More water gives a more dilute solution that is easier to measure in fine increments; less water gives a more concentrated solution in less liquid.
In practice BPC-157 is reported to reconstitute readily and to go fully into solution within a few minutes, yielding a clear, colorless liquid. The powder is generally well behaved and does not have a strong tendency to gel or precipitate at these modest concentrations, so a solution that stays cloudy, shows floating particles, or changes color after mixing is treated as a sign of a problem rather than a normal state. To help it dissolve cleanly, the water is added slowly down the inner glass wall of the vial rather than jetted directly onto the powder cake, and the vial is swirled gently rather than shaken, since vigorous shaking foams the liquid and the air-liquid interface can degrade peptide molecules. After mixing, the solution is inspected for full clarity before use, and it is kept out of direct light.
Handling and storage
Store the reconstituted vial refrigerated at 2 to 8 degrees Celsius and keep it out of light. Wipe the rubber stopper with an alcohol swab before each puncture. Label the vial with the mix date so its age can be tracked. A refrigerated working window of roughly four weeks (about 28 days) is commonly cited for solutions made with bacteriostatic water. Discard any vial that becomes cloudy or discolored, or that shows floaters or particulates.
Related reading
Tools and supplies
- Reconstitution & blend calculators
- Bacteriostatic Water 30 ml
- Gansulin Metal Reusable Pen
- 3 ml Glass Cartridges (10-pack)
- Complete Starter Kit
For laboratory and research reference only. Educational content, not medical, dosing, injection, or therapeutic guidance, and not intended for human or animal use. Any research uses described are investigational and not confirmed or approved benefits. Confirm anything involving health with a licensed professional. References linked above.