Ovagen
What it is
Ovagen is a synthetic short-chain peptide, described in most references as the tripeptide Glu-Asp-Leu (EDL). It belongs to the Khavinson class of peptide bioregulators, a group of ultra-short peptides associated with the Saint Petersburg Institute of Bioregulation and Gerontology that are grouped by the specific tissue each is said to target.
Research context and categorization
Ovagen is categorized as a liver and gastrointestinal tissue bioregulator within the broader Khavinson bioregulator family. In the model proposed for these peptides, short amino acid sequences are described as interacting with DNA and chromatin to influence tissue-specific gene expression. That mechanism is a research hypothesis rather than a settled fact.
In neutral research terms, Ovagen is commonly discussed in relation to hepatic (liver) tissue and gastrointestinal epithelium. It has been investigated in the context of age-related changes in liver structure and function, liver tissue maintenance, and gastrointestinal barrier markers such as tight-junction proteins in aged tissue models. It is studied in the context of hepatic and digestive homeostasis rather than as a treatment for any condition.
These uses are investigational. Ovagen is not FDA-approved, and the effects described in preliminary, largely non-Western literature are not confirmed or established benefits. Statements that it treats, reverses, or cures any liver or digestive condition should be treated as unproven.
Status
- Regulatory status: Research-only. Ovagen is not FDA-approved for any indication and is not an approved drug, food, cosmetic, or dietary supplement. It is characterized largely in preclinical work with no published human clinical trials.
- Sport status: Not specifically listed on the WADA Prohibited List by name. Athletes should note that WADA prohibits broad categories such as peptide hormones, growth factors, and related substances, and that the list includes catch-all language covering compounds with similar structure or biological effect. Because Ovagen is a non-approved research peptide, its standing under those broader categories can be ambiguous, so anyone subject to testing should verify current WADA guidance directly.
Reconstitution notes (general)
Lyophilized (freeze-dried) peptides are prepared by adding bacteriostatic water to the vial. The resulting concentration is a simple ratio: concentration equals the milligrams of peptide in the vial divided by the millilitres of bacteriostatic water added. For example, a 20 mg vial reconstituted with 2 mL of bacteriostatic water gives 10 mg/mL. You can work out any combination with the calculator at our reconstitution and blend calculators.
Dilution and handling notes (compound-specific)
Ovagen is supplied as a lyophilized powder, most commonly in a 20 mg vial. A typical reconstitution range is roughly 1 mL to 3 mL of bacteriostatic water per 20 mg vial, which corresponds to about 20 mg/mL down to around 6.7 mg/mL. Adding 2 mL to a 20 mg vial is a common choice because it yields a round 10 mg/mL that is easy to measure.
As a very small tripeptide, Ovagen is highly water-soluble. It generally goes into solution readily and cleanly, giving a clear, colorless liquid, and it does not have the tendency to gel, cloud, or turn stringy that some larger or more hydrophobic peptides show when concentrated. To keep the solution clean, add the water slowly down the inner wall of the vial rather than directly onto the powder, and swirl gently instead of shaking to limit foaming. If any faint haze remains right after adding water, a short rest at room temperature usually clears it as the last of the powder dissolves. Powder that will not clear, or a solution that turns cloudy later, is a sign to discard rather than force back into solution. More dilute mixes are easier to measure accurately; more concentrated mixes reduce the total liquid volume.
Handling and storage
Store the reconstituted vial refrigerated at 2 to 8 degrees C, kept out of direct light. Wipe the rubber stopper with an alcohol swab before and after drawing from it, and label the vial with the mix date. Treat a reconstituted vial as usable for roughly a four-week refrigerated window. Discard the vial if the contents become cloudy or discolored, or if particles or floaters appear. Lyophilized, unmixed vials are best kept cold and protected from light until use, and repeated freeze-thaw cycles of the mixed solution should be avoided.
Related reading
Tools and supplies
- Reconstitution & blend calculators
- Bacteriostatic Water 30 ml
- Gansulin Metal Reusable Pen
- 3 ml Glass Cartridges (10-pack)
- Complete Starter Kit
For laboratory and research reference only. Educational content, not medical, dosing, injection, or therapeutic guidance, and not intended for human or animal use. Any research uses described are investigational and not confirmed or approved benefits. Confirm anything involving health with a licensed professional. References linked above.