HCG (Human Chorionic Gonadotropin)
HCG (Human Chorionic Gonadotropin) is a research reference peptide composed of 237 amino acids total (alpha: 92 aa + beta: 145 aa). Structural class: Heterodimeric glycoprotein with two non-covalently linked subunits. Reported molecular weight: 36,700 Da (36.7 kDa). Listed for research and educational reference only.
| Also known as | Gonadotropin Hormone, LH Receptor Agonist |
|---|---|
| Evidence level | FDA Approved |
| Regulatory status | FDA-approved |
| Molecular weight | 36,700 Da (36.7 kDa) |
| Chain length | 237 amino acids total (alpha: 92 aa + beta: 145 aa) |
| Class | Heterodimeric glycoprotein with two non-covalently linked subunits |
| Sequence | Alpha subunit (92 aa): identical to LH, FSH, and TSH alpha subunits. Beta subunit (145 aa): unique to HCG with 24 aa C-terminal extension not found in LH. Heavy glycosylation (~30% carbohydrate content) |
| Notes | Extensive N-linked and O-linked glycosylation, The glycan chains extend half-life and influence receptor binding, Urinary-derived (e, g, Pregnyl) vs recombinant (e, g, Ovidrel) for |
| Updated | 2026-10-12 |
For research and educational reference only.