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What it is
CJC-1295 with Ipamorelin is the most widely compounded growth-hormone-axis blend. It pairs a GHRH analog (CJC-1295) with a growth-hormone secretagogue / GHRP (Ipamorelin).
Key point: This combination pairs a GHRH analog with a GHRP to target two different mechanisms of growth hormone release, which is studied for a larger, cleaner pulse than either alone.
Why these are combined
How the Combination Works
The two act on different arms of GH release. CJC-1295 supports a sustained GHRH signal, while Ipamorelin triggers a discrete GH pulse and is noted in research for being relatively selective (less effect on cortisol or prolactin than older GHRPs).
A GHRH analog plus a GHRP is studied for a larger, cleaner pulse than either alone, which is why this specific pairing dominates the compounding world.
The components
- CJC-1295 — a GHRH analog studied for sustained growth-hormone-releasing signaling.
- Ipamorelin — a selective GHRP / secretagogue studied for a clean GH pulse.
Reconstitution and blending
Both are lyophilized and reconstituted with bacteriostatic water; they are commonly co-drawn. The DAC and no-DAC (Mod GRF 1-29) forms of CJC-1295 differ in half-life, which changes how a blend is timed.
Our reconstitution and DIY blend calculators handle the per-cartridge volumes and beyond-use timing once you have decided what shares a cartridge.
Status in sport
Both components are prohibited in sport under WADA S2 (peptide hormones, growth factors, releasing factors and secretagogues), prohibited at all times.
Related reading
- CJC-1295
- Ipamorelin
- Full peptide reference library and stacking guide
- Reconstitution and blend calculators
Reminder: research and educational reference only. Preppin Peppers sells hardware and materials, not peptides. Not medical, dosing, or health advice, not evaluated by the FDA, and not intended for human or animal use.
